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ISO 13485:2016Medical Devices5 months

Medical Device Company Passes ISO 13485 Audit with Zero Non-Conformances

0
Non-Conformances
5 Months
Time to Certification
3 Mo. Post-Cert
510(k) Submission
25%
Dev Cycle Reduction

The Challenge

A growing Class II medical device manufacturer needed ISO 13485:2016 certification as a prerequisite for FDA 510(k) submission. The company had tripled its workforce in 18 months but had never operated under a formal quality management system. Documentation was inconsistent, design controls were ad hoc, and there was no CAPA process. With investor pressure to reach market within 9 months, every week of delay had direct financial consequences.

Our Approach

1

Performed an end-to-end assessment of the existing quality practices against ISO 13485:2016 and FDA 21 CFR Part 820, identifying 62 gaps across 8 critical process areas.

2

Designed a fit-for-purpose QMS architecture that met both ISO 13485 and FDA requirements simultaneously, avoiding the need for costly rework during 510(k) preparation.

3

Built a complete Design History File (DHF) framework with design input/output controls, verification & validation protocols, and design review stage gates.

4

Implemented a risk management process per ISO 14971, including a product-level risk management file with hazard analysis, risk evaluation, and residual risk assessment.

5

Established a CAPA system with root cause analysis methodology (8D framework), effectiveness verification, and trend analysis capabilities.

6

Trained 22 employees across production, engineering, and quality on the new QMS, with role-specific competency assessments.

The Results

Achieved ISO 13485:2016 certification with zero non-conformances — no majors, no minors.

Built a dual-purpose QMS that satisfied both ISO 13485 and FDA 21 CFR Part 820 requirements.

FDA 510(k) submission completed 3 months after certification, directly leveraging the ISO 13485 QMS documentation.

Design control process reduced product development cycle time by 25% through structured stage-gate reviews.

First CAPA processed and closed within the new system within 30 days of go-live, demonstrating immediate system effectiveness.

100% employee training completion with documented competency verification.

Exceleor didn't just help us check a box — they built a quality system that our FDA consultant said was the most organized 13485 implementation she'd reviewed. Zero non-conformances on the first audit was something we honestly didn't think was possible for a startup.
VP of Quality & RegulatoryClass II Medical Device Manufacturer

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